Copper(I)-Catalyzed Caryl-Calkynyl Bond
Formation of Aryl Iodides with Terminal Alkynes

K. G. Thakur; G. Sekar

doi:10.1055/s-0029-1216876

PAPER

Copper(I)-Catalyzed C_aryl-C_alkynyl Bond Formation of Aryl Iodides with Terminal Alkynes

K. G. Thakur, G. Sekar*
Department of Chemistry, Indian Institute of Technology Madras, Chennai, Tamil Nadu 600036, India
Fax: +91(44)22574202; e-Mail: gsekar@iitm.ac.in;

Abstract

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Abstract

A wide range of internal alkynes are synthesized from the corresponding aryl iodides and terminal alkynes by Sonogashira-type cross-coupling reactions through C_aryl-C_alkynyl bond formation in the presence of a catalytic amount of readily available DBU-CuBr complex under mild reaction conditions.

Key words

copper catalyst - coupling reaction - arylated alkynes - C-C bond formation - Sonogashira coupling - nitrogen ligands

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References

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Copper(I)-Catalyzed Caryl-Calkynyl Bond Formation of Aryl Iodides with Terminal Alkynes

Copper(I)-Catalyzed C_aryl-C_alkynyl Bond Formation of Aryl Iodides with Terminal Alkynes